Mechanisms of Retinal Damage after Ocular Alkali Burns

Topical steroid use in the treatment of ocular alkali burns.

BACKGROUND Ocular alkali burns can be associated with a poor visual outcome. The release of collagenases and proteases after the injury leads to corneoscleral melting. The role of topical steroids in such patients is controversial as they have been postulated to exacerbate corneoscleral melting. METHODS 30 patients were reviewed retrospectively after admission to King's College Hospital with ...

Outcomes of an algorithmic approach to treating mild ocular alkali burns.

The OCT angiograms showed reduced CNV flow area and CNV vessel loss following treatment. Because retinal vessel density did not decrease, reduced areas of CNV flow likely represent therapeutic effect. Optical coherence tomographic angiography can also be used to evaluate blood flow of the choriocapillaris. In healthy eyes, the choriocapillaris appears confluent on OCTangiograms.4 In this case, ...

Chemical Ocular Burns - Preamble

Ultrashort Laser Retinal Damage Threshold Mechanisms

Ultrashort laser pulses have been adapted for use in a variety of applications from micromachining of dielectrics to atmospheric spectrochemistry and multiphoton microscopy. These lasers emit almost exclusively in the retinal hazard wavelength regime, making them potential sources for accidental vision loss, but also candidates for biomedical applications where precise alteration of tissues is ...

Severe burns from alkali drain cleaner.

TO THE EDITOR: Alkali drain cleaner has previously been reported to cause oral, oesophageal and cutaneous burns. 1-4 The risk of these cleaners causing full thickness cutaneous burns in children needs to be emphasised. Two toddlers recently presented to our hospital with severe burns after exposure to alkali drain cleaning products. An 18-month-old boy opened the box and bit open the silver foi...